This course provides a practical overview of differentiated vulvar intraepithelial neoplasia (dVIN), a clinically significant precursor to vulvar squamous cell carcinoma that often arises in a background of chronic inflammatory dermatoses such as lichen sclerosus. Through a real clinical case, you'll learn how to recognise suspicious vulvar lesions, understand the importance of appropriate biopsy, and identify the key histological features that support a diagnosis of dVIN. The course also explores the critical role of clinicopathologic correlation and early recognition in preventing progression to invasive malignancy.
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Recognising suspicious vulvar lesions in patients with chronic lichen sclerosus
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Understanding the differences between differentiated VIN and HPV-associated vulvar dysplasia
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Key histological features supporting a diagnosis of differentiated VIN
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The role of p53 immunohistochemistry in confirming diagnosis
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Appropriate biopsy techniques for suspicious vulvar lesions
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Clinicopathologic correlation and its importance in diagnosis
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Identifying treatment-resistant or atypical lesions requiring further assessment
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Timely specialist referral and multidisciplinary management
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Preventing progression to invasive squamous cell carcinoma through early recognition
